The safest way is through a program set up to dispose of these items. Contact your local Walgreen’s Drug Store to participate in their Needle Collection & Disposal System to properly dispose of used needles. At home, place the used needle in a sturdy plastic container such as a detergent bottle. Place the lid on the bottle, securely tape it closed, mark NEEDLES on all sides of the container and put in your trash. Keep the safety of the trash collectors when using this method and prepare the container with extra caution.